Yes, I think it is worth trying low-dose naltrexone in fibromyalgia - seems safe and may be effective.

There have been a few small reports suggesting the efficacy of naltrexone in fibromyalgia and other chronic pain, however, more evidence is sorely needed. I would suggest looking for any current studies to enroll prospective patients or at the very least, consulting with a pain management expert.

I find the drug somewhat helpful but hard to distinguish from the placebo effect. The results are not dramatic. I use a compounding pharmacy and start with 1.5mg daily for a week and then increase to a maximum of 6mg daily. Since most of my patients are taking several other medications it is difficu...

I have done this, acknowledging the paucity of data to the patient and the issues involved. Patients must be counseled to be off (and avoid) other opioids, including tramadol. The patients need to know that the medication will come from a compounding pharmacy, so s/he will end up going to a differen...