Would you consider using transdermal estrogen in a patient with “high risk” APLS patient on warfarin?

Both VTE and arterial thrombosis (CVA) prior to starting warfarin. Lupus anticoagulant positive. Has severe post menopausal symptoms.

Answer from: at Community Practice

Given her clinical diagnosis of high-risk APS, I would first trial nonhormonal therapies or progesterone only therapies for management of her post-menopausal symptoms. Current ACR guidance recommends against hormone replacement therapy in patients with APS on anticoagulation (Sammaritano etl al Arth...

Comments

at The Mass General Porphyria Center
Just had a similar patient. Starting transdermal e...

Medical Oncologist at Hematology & Oncology-Southeast Iowa Regional Medical Center
I have a similar patient but wants Estrogen therap...

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Would you consider using transdermal estrogen in a patient with “high risk” APLS patient on warfarin?

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