Would you continue or stop anticoagulation for a DVT/PE in a patient with active cancer who has completed 6 months of therapy?

This is an important question that we didn’t really have a clear answer for… until this year when an NEJM RCT was published!

In this RCT, patients with cancer-associated VTE who completed 6 months of full-dose apixaban were randomized to half-dose apixaban vs. full-dos...

Important information. Very nice that the information is recent and finds that half-dose Eliquis is sufficient after treatment of VTE in cancer patients.

My concern is that if active cancer is the cause of her/his DVT/PE, so as long as the cancer remains active, the risk for DVT/PE remains elevated. The RCT was only done up to 12 months, so we have no data beyond that. I will be careful in reducing anticoagulation in patients with active cancer who h...