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Would you discontinue or dose-reduce tamoxifen in a patient who developed hepatic steatosis?

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How would you manage a patient that developed hepatic steatosis while on tamoxifen?

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1 Answer
Mednet Member
Mednet MemberInvited Expert
Medical Oncology · Ohio State University
Answered on

In the absence of liver enzyme elevation and other risk factors for developing hepatic steatosis (such as obesity and dietary habits), I would be comfortable continuing tamoxifen. However, if tamoxifen-associated hepatic injury is suspected, my preference would be to discontinue tamoxifen or change ...

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