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Would you dose-escalate the radiation prescription for patients with radioresistance SNP's in ERCC1 or ERCC2?

For example, in locally advanced NSCLC would you dose-escalate beyond 60 Gy?
1 Answer
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Radiation Oncology · The University of Hong Kong
Answered on

The current practice does not require testing of ERCC1 or ERCC2 SNPs, so such data is not available for us in the clinic. I am not sure if I can order such a test in the practice and if the Health Insurance would cover such test.

Using this biomarker signature, we are going to open a trial to optim...

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