Would you ever consider prophylactic anticoagulation in patients with CKD requiring ESA therapy?

Would you consider prophylactic anticoagulation in a patient with CKD and history of unprovoked VTE when starting ESA therapy?

• No, I would not offer ESA to begin with
• No, I would offer ESA with intensive risk/benefit discussion
• Yes, I would consider low-dose apixaban as prophylaxis if the patient had an existing past indication to consider indefinite anticoagulation
• Yes, I would consider warfarin as prophylaxis if the patient had an existing past indication to consider indefinite anticoagulation