Would you ever utilize quad shot specifically for a large SNUC?

The Quad Shot is palliative, while even in advanced SNUC definitive chemo-RT provides a chance for about 50% LR control at 2 years and long-term cure in 22% of patients. This is based on our results in 19 patients, almost all of whom had Kadish stage C or AJCC T4. In our experience, a surgical attem...

Not a big fan of "quad shot", personally. Definitely not in a large SNUC. If the intent is to stop bleeding, then a conformal short palliative course may suffice.