Would you favor post op radiation therapy for soft tissue sarcoma if a positive margin were still expected despite pre-op radiation?
Tumor factor: Large axillary soft tissue sarcoma with involvement of the brachial plexus
Other factor: Surgery would like to pursue upfront surgery to debulk tumor as tumor not expected to shrink significantly with pre op radiotherapy
2 Answers
Mednet MemberInvited Expert
Radiation Oncology · The Ohio State University - James Cancer Hospital and Solove Research Institute
Answered on · Updated on
- The key question here is whether you are dealing with tumor ON the plexus, expected to result in a microscopically positive (R1) margin, or tumor IN the plexus, expected to result in gross residual disease (R2).
- If tumor is ON the plexus, a planned R1 margin on a critical structure, with addition o...
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Mednet Member
Radiation Oncology · Rush University Medical Center
Answered on
In responding to this question, we are limited by the following:
- Absence of MRI images.
- Specific information about size, histology, and tumor grade.
- No information regarding patient's age, other morbidity, or relevant past medical history. Although I assume the patient in question is an adult if thi...
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