Would you give a second round of therapeutic RAI in a patient with PTC s/p total thyroidectomy and I-131 ablation who is found to have recurrent disease in cervical lymph nodes s/p repeat neck dissection?

There is very limited clinical information provided.

Thoughts and possible direction for further work up.

1. RAI is not routinely indicated after cervical "recurrence" in a previously RAI-treated patient.
2. Also depends on the extent of residual cancer status post-recent neck dissection surgery. What wa...

I agree with Dr. @Dr. First Last. The decision to give additional RAI is dependent on the results of the second surgery (positive margins? extranodal extension? all known diseases removed successfully?), the post-operative TG, and whether other imaging has indicated that residual thyroid cancer may ...