Would you give adjuvant endocrine therapy to a premenopausal woman with early stage node positive breast cancer that was ER negative, PR positive (60%) and HER2 positive?
She achieved PCR with NAC with TCHP and is now on adjuvant HP.
2 Answers
Mednet MemberInvited Expert
Medical Oncology · H Lee Moffitt Cancer Center, University of South Florida
Answered on
The first thing I would do in this case is have the block retested for ER staining preferably at a different lab. There have been multiple studies published in the past that have shown ER negative PR positive tumors (particularly strong PR staining like this one) frequently end up being ER+ on retes...
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Mednet Member
Medical Oncology · The Center for Hematology and Oncology at Holy Cross Hospital
Answered on
Would give only anti HER2 therapy.
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