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Would you give adjuvant immunotherapy after nephrectomy?

Is DFS benefit in KN-564 in ASCO2021 sufficient evidence to change practice?
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Will you give adjuvant pembrolizumab to patients with high risk RCC after nephrectomy?

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1 Answer
Mednet Member
Mednet MemberInvited Expert
Medical Oncology · Vanderbilt-Ingram Cancer Center
Answered on

The KN-564 will certainly change the landscape of adjuvant RCC. Prior studies had either been negative, or have been positive (sunitinib in S-TRAC) but with toxicity that has precluded widespread use. The OS data from KN-564 is too immature to interpret, in my opinion, so the debate of whether to tr...

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