Would you give chemotherapy to a fit patient with myxoid liposarcoma of the knee that is resectable with adverse functional outcomes who will be undergoing neoadjuvant radiation and resection?

Topics: Sarcoma • Medical Oncology

If yes, would you offer neoadjuvant or adjuvant, concurrent or sequential?

Answer from: Medical Oncologist at Academic Institution

I give ifosfamide to people with myxoid/round cell liposarcoma.In general, I do not give adjuvant chemotherapy to adult-type soft tissue sarcomas because of the phase 3 EORTC studies showing that it did not improve survival.Le Cesne et al., PMID 25294887 But I do give ifosfamide to people with ...

Comments

Medical Oncologist at Texas Oncology
Thank you for the detailed explanation.

Medical Oncologist at Ironwood Cancer & Research Centers
Thank you for this explanation. In an elderly pati...

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