Would you offer a palliative or more aggressive course of radiation therapy for a symptomatic isolated supraclavicular recurrence of a squamous cell carcinoma of the esophagus?

Such early disease progression suggests there was likely occult involvement of the supraclavicular lymph node at the time of initial diagnosis. My decisions on management would hinge upon the extent of initial CRT field.

If the supraclavicular lymph node was in field, I would favor a systemic treatme...

Before I decide on how to manage the patient, I would want to know the following:

• In retrospect, was there a supraclavicular node on the radiation planning CT that could be deemed responsible for the new recurrence/progression?
• What chemoradiation regimen was given to the patient, including the te...

Palliative.