Would you offer adjuvant chemotherapy/immunotherapy for resected pure squamous cell carcinoma (T2-T4 or N+/-) of the renal pelvis?
If you do recommend adjuvant therapy, what regimen would you use?
Answer from: Medical Oncologist at Community Practice
There are no definitive data in the setting of adjuvant therapy for high-risk (>=pT3 or N+) predominant or pure squamous cell carcinoma of the urinary tract who have undergone upfront definitive surgery. Given the locoregional recurrence risk is quite important in squamous cell carcinoma, adjuvan...
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Answer from: Medical Oncologist at Academic Institution
Primary or pure squamous cell carcinoma of renal pelvis is very rare and the role of adjuvant therapy after surgery is unknown. Squamous cell carcinomas in head-neck, anal and other sites, tend to recur locally. Based on that behavior, I would offer radiation with a sensitizer, preferably week...