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Would you offer adjuvant pembrolizumab to a stage II-III adenocarcinoma of the lung who had a complete pathologic response to 4 cycles of cisplatin/pemetrexed/pembro (KN-671)?

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Mednet Member
Mednet Member
Medical Oncology · Indiana University School of Medicine

The question posed is a central question of investigation and debate today.

In my view, the patients most likely to derive benefit from adjuvant immunotherapy after receiving neo-adjuvant chemo-immunotherapy are those with the best responses to neo-adjuvant therapy. The patients I would least likely ...

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Mednet Member
Mednet Member
Medical Oncology · Mary Lanning Healthcare Morrison Cancer Center/University of Nebraska Medical Center Adjunct Faculty

For perioperative systemic therapy of NSCLC, current NCCN guidelines recommend neoadjuvant chemoimmunotherapy if patients are eligible for immune checkpoint inhibitors; the two listed options include either neoadjuvant nivolumab and platinum doublet chemotherapy every 3 weeks for 3 cycles followed b...

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Would you offer adjuvant pembrolizumab to a stage II-III adenocarcinoma of the lung who had a complete pathologic response to 4 cycles of cisplatin/pemetrexed/pembro (KN-671)? | Mednet