Would you offer adjuvant radiation therapy in a young adult with NF1 who has a craniopharyngioma s/p STR?

In NF1 patients, radiation therapy for craniopharyngioma has been associated with vascular damage and Moya Moya syndrome. On the other hand, subtotally resected craniopharyngiomas have a high chance of recurrence. It has been shown that, dosimetrically, intensity-modulated proton therapy (IMPT) coul...

In treating a young adult with NF1 and residual craniopharyngioma following a subtotal resection (STR), my approach would be the same, regardless of the presence of NF1 mutation or NF1 syndrome. If the STR has alleviated presenting symptoms, the patient is compliant with follow-up, and there are no ...