Would you offer adjuvant radiation to a patient with a vaginal spindle cell sarcoma s/p modified radical hysterectomy with bilateral sapingoopherectomy with negative margins?  

Final pathology showed grade 3 spindle cell sarcoma of thee vagina involving the anterior lateral cervix 5.6cm x 4.5 x 3.4cm, <0.1cm left lateral margin. No nodal sampling was performed. 

Would you consider EBRT to 45Gy + cuff brachy boost, or observe similar to a retroperitoneal sarcoma?



Answer from: Radiation Oncologist at Community Practice
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Radiation Oncologist at Washington VAMC
The patient had an MRH and BSO with the close marg...
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