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Would you offer adjuvant radiotherapy for a malignant fibromyxoid tumor of soft tissue with margin < 1 cm on re-excision?

Adverse features include increased nuclear size, nuclear atypia, and mitotic activity up to 10/50 HPF.
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Would you offer adjuvant radiotherapy for a malignant fibromyxoid tumor of soft tissue with margin < 1 cm on re-excision?

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2 Answers
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Mednet MemberInvited Expert
Radiation Oncology · Cleveland Clinic Florida
Answered on

Malignant ossifying fibromyxoid tumors are very rare and from a pathologic perspective, often get lumped under the tumors of intermediate malignant potential and of uncertain differentiation category.

The expectation that the histologically malignant fibromyxoid tumors behave malignant, and thus I w...

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Mednet Member
Mednet MemberInvited Expert
Radiation Oncology · University of Florida
Answered on

No if grade 1-2. Yes if grade 3. So likely no.

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