Would you offer any additional adjuvant therapy after platinum based chemotherapy for patients with resected PD-L1 positive Stage II-III lung adenocarcinoma with EGFR exon 20 insertions?

Topics: Thoracic Malignancies • Medical Oncology

Answer from: Medical Oncologist at Academic Institution

At this time, I would likely offer adjuvant immunotherapy as in KEYNOTE-091 NCT02504372 (pembrolizumab) or IMpower010 (atezolizumab). Though EGFR ex20ins mutations occur mainly in non-smoking patients with NSCLC, a population that tends to benefit less from immunotherapy, there is little data to sug...

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Medical Oncologist at SSM Cancer Care
Thanks a lot. Appreciate you took the time to ans...

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