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Would you offer any adjuvant therapy for cervical cancer following total pelvic exenteration in the setting of a positive pelvic lymph node?

Previously received pelvic EBRT and intracavitary brachytherapy. IORT was administered to the node-positive side wall at the time of exenteration.
3 Answers
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Radiation Oncology · University of Kentucky
Answered on

I am going to "eat a bit of crow" here and admit to having been schooled a bit by the esteemed Dr. @Dr. First Last. I admit to having immediately jumped to the post-rad hyst situation rather than post-exenteration, and I agree that the radicality of the operation could factor into the decision about...

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Gynecologic Oncology · Medical University of South Carolina
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A study several decades old noted that with one positive node at time of exent, those patients did just as well as if negative nodes would follow.

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Radiation Oncology · University of Kentucky
Answered on

I have to respectfully disagree with Dr. @Dr. First Last. The very old study that he refers to was certainly not powered to answer this question, as it was simply a subset analysis with small numbers. In subsequent studies by the GOG, patients with single positive pelvic nodes were eligible for stud...

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