Would you offer consolidation RT to a young woman with bulky mediastinal DLBCL who achieved early and persistent CR to RCHOP on PET?
Answer from: Radiation Oncologist at Academic Institution
Dr. @Christopher R. Kelsey has modestly omitted one salient trial in his answer, namely the Duke trial which he led evaluating low dose consolidation RT (20 Gy) following CR to induction chemotherapy, i.e. PET negative response (Kelsey et al., PMID 30858144). To recapitulate briefly, 62 patients wit...
Sign in or Register to read more
Answer from: Radiation Oncologist at Community Practice
I would like to know a bit more about the extent of the disease, the number of cycles of R-CHOP delivered, and when CR was achieved.Assuming that this patient had an early stage (I-II) DLBCL with the only risk factor being "bulky disease" and achieved CR in the PET during chemotherapy (interim) and ...
Comments
Radiation Oncologist at Duke University Medical Center
Studies in the PET-CT/Rituximab era evaluating the...
Studies in the PET-CT/Rituximab era evaluating the...
Radiation Oncologist at University Hospital Basel
Thank you for bringing up the RICOVER-60/RICO...
Thank you for bringing up the RICOVER-60/RICO...