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Topics:
Gastrointestinal Cancers
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Medical Oncology
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Pancreatic Cancer
Would you offer Gemcitabine/Cisplatin (or other platinum-based regimens) for metastatic pancreatic cancer harboring somatic ATM mutations?
NCCN indicates only BRCA1/2 and PALB2 mutations
Related Questions
How would you approach a locally advanced ampullary carcinoma with BRCA1 mutation whose Whipple showed complete pathologic response after 5 cycles of neoadjuvant mFOLFIRINOX?
Would you offer consolidative full dose chemo-RT for local residual pancreatic disease in a patient with stage IV pancreatic adenocarcinoma with excellent response after induction chemotherapy?
Should immunotherapy be added to standard of care neoadjuvant chemotherapy in borderline resectable MSI-H adenocarcinoma of pancreas?
How long should surgery be delayed in a patient with localized, resectable pancreatic cancer who developed acute pancreatitis following EUS guided biopsy?
What are your top takeaways in GI Cancers from ASCO 2023?
Do you offer a curative surgery (Whipple procedure) to patients with duodenal adenocarcinoma, with 2-5 liver metastases, and with near CR after 3-6 months of FOLFOX chemotherapy?
How would you approach a stage II colon cancer with negative ctDNA but markedly elevated CEA level post-colectomy?
For inoperable cholangiocarcinoma, do you recommend up-front chemotherapy prior to offering SBRT or combination chemoradiation?
How do you approach a low grade intra-cholecystic papillary neoplasm of the gallbladder without invasive component and reported surgical pathology with negative margins ?
Would you recommend off-label use of chemoimmunotherapy for metastatic anal squamous cell cancer?