Would you offer pelvic re-irradiation in the setting of locally recurrent anal cancer in the presacral region?

Re-irradiation is always tricky. I don't want to miss a chance to help someone, and I really don't want to hurt someone. With re-irradiation, the devil is in the details. If it is small, in a spot where symptomatic toxicity is less likely, and a long period of time has passed since the original chem...

This is a complicated topic with a number of different options. Aggressiveness of treatment relates both to disease status and timing of prior lines of therapy. Also, as Dr. Schroeder and Dr. Horne have pointed out, the size and location of the mass are important. Our preference is to retreat prior ...