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Would you offer PMRT to an ER/PR positive HER2 amplified early stage (node negative) breast cancer patient found to have less than pCR to neoadjuvant TCHP?

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Mednet Member
Mednet Member
Radiation Oncology · Varian Medical Systems/Allegheny health network

With TCHP, expected pCR is rare (around 25 to 30 percen) for ER positive breast ca and they derive benefit from anti estrogen therapy and I would not offer PMRT

Only one with node negative but less than pCR would consider for PMRT is triple negative especially if residual disease is more than 2 cm

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