Would you offer preoperative radiation for an intrathoracic leiomyosarcoma in the posterior mediastinum?   

I would want further details (age, grade, size, specific anatomic relationships, etc), but most likely yes. DOSE AND FIELD: I would typically treat GTV + 1.5 cm anatomically constrained expansion to 50.4/28, plus any suspicious edema on T2 STIR. By analogy with retroperitoneal sarcomas, I think...