Would you offer reirradiation for a patient who had prior MammoSite PBI?
The patient had ER/PR positive, early-stage recurrent disease superficial to the prior RT site involving the nipple and dermis without ulceration, totally resected with lumpectomy.
Would you be inclined to offer re-irradiation in this setting: if so, would you treat whole breast or partial breast in the setting of re-irradiation, and what would be your preferred dose and fractionation scheme?
2 Answers
Mednet MemberInvited Expert
Radiation Oncology · Varian Medical Systems/Allegheny health network
Answered on
Based on the effect of the previous RT, I have treated and favored 40 in 15 whole breast.
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Mednet MemberInvited Expert
Radiation Oncology · Allegheny Health Network, Pittsburgh
Answered on
I would consider re-irradiation but would counsel on the risk of toxicity including healing/wounds given dermis involvement. If treating, I would consider 40/15 partial if > 5 years from RT but whole breast can also be considered (brachy was used as boost on previous WBI trials, though at lower dose...
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