Would you offer salvage chemotherapy to a patient with stage IIIC poor risk NSGCT in whom AFP fail to normalize even after 2 months of completion of 4 cycles BEP?

Topics: Genitourinary Cancers • Medical Oncology • Testicular Cancer

Residual disease with bulky retroperitoneal masses also present on scans

Answer from: Medical Oncologist at Community Practice

It depends on the absolute value and the trend of elevated AFP. Low level AFP elevation (usually in the teens) is common and difficult to accurately interpret the abnormality. If the AFP is not rising, I probably proceed to post-chemo RPLND as the first step. Also, sometimes people proceed to chemot...

Comments

Medical Oncologist at Chaparral Medical Group
Thanks. Can you please define poor risk settings w...

Medical Oncologist at Testicular Cancer Commons
If the AFP is increasing on several determinations...

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