Would you offer salvage radiation for a local recurrence of prostate cancer that was initially treated with SBRT?

At this time, I’m not sure there is enough data to recommend a course of re-irradiation after primary SBRT outside of a clinical trial, although I do know some who offer it. The majority of the data regarding re-irradiation for local recurrence after RT comes from smaller retrospective reports, although there are a few notable prospective trials that have been reported for re-irradiation with external beam (e.g., NCT00851916, NCT03438552, NCT03073278, NCT03253744) and brachytherapy (e.g., RTOG 0...