Would you offer systemic therapy before or after resection of an axillary-only recurrence of triple negative breast cancer?

I would most likely consider the neoadjuvant approach. - of course, few things to consider prior to making a decision.

1. How long was the duration between the previous completion of therapy for her first breast cancer? And was previous therapy complete, or rather was incomplete therapy was given?

2...

I agree with @Dr. First Last. The CALOR trial supports administration of chemotherapy in TNBC patients with a locoregional recurrence. Assuming there is no evidence that the axillary recurrence is biologically different from the breast primary, neoadjuvant chemotherapy will allow you to assess the s...