Topics:
Breast Cancer • Radiation Oncology
Would you omit a lumpectomy boost in a younger patient (<50 y) with a primary tumor that is otherwise favorable?
Is age solely indication for boost irrespective of other factors?
Answer from: Radiation Oncologist at Academic Institution
This is certainly an evolving area, but I do routinely offer boost solely based on younger age (< 50 or < 40) in patients with otherwise favorable features (ex. T1N0 ER+/PR+/HER2-).
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Answer from: Radiation Oncologist at Academic Institution
This is a great question worthy of further study. It's important to note that in the EORTC boost trial, assessment of margins for DCIS was not required. In addition, premenopausal patients did not receive endocrine therapy. The emerging data suggest that biology is key in young and older patients. I...
Answer from: Radiation Oncologist at Academic Institution
No.
Answer from: Radiation Oncologist at Community Practice
As more data emerges from the genomic test and local control we may be guided by risk category to decide boost or not in ER-positive breast cancer in < 50 years.
Answer from: Radiation Oncologist at Community Practice
Several years ago there was a retrospective review of the Whelan AFWBRT Study which did not include a boost.
The UToronto-Sunnybrook reviewed actual treatments of DCIS patients enrolled in the protocol and found some patients did receive a boost even though the protocol did not allow it. I th...
Comments
Radiation Oncologist at Cleveland Clinic
With hypofractionated WBI I use 10 Gy/4-5 fraction...
With hypofractionated WBI I use 10 Gy/4-5 fraction...
Radiation Oncologist at Angelhaven LLC
Agree, and that is what most do. The paradox...
Agree, and that is what most do. The paradox...