Would you perform plasmapheresis for an ABO-incompatible kidney transplant recipient who has titers of 1:16 and a stable creatinine 3 months post-transplant?

I would not perform plasmapheresis for an ABO-incompatible patient with titers of 1:16 (which are not that high and presumably IgG) based on the stable kidney function. At this point, there should be "accommodation" of the graft to anti-blood group antibodies and there is no need to check titers this far post-transplant.

Totally agree with Dr. @Dr. First Last that there is no need to check titers that far posttransplant with stable kidney allograft function and therefore there is no need to perform pheresis to bring down the titers.