Would you recommend administering IV amino acids prior to cardiac surgery with cardiopulmonary bypass, given recent trial findings of improved AKI rates but no significant difference in kidney-replacement therapy with IV amino acids?
Landoni et al., PMID 38865168
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Would you consider administering IV amino acids before cardiac surgery with cardiopulmonary bypass to reduce the risk of post-operative acute kidney injury in light of recent trial findings?
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1 Answer
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Nephrology · The University of Texas Health Science Center at San Antonio
Answered on
The trial by Landoni et al., PMID 38865168 in the August NEJM examined the effect of an amino acid infusion (2g/kg/day) in patient undergoing cardiac bypass surgery. They found a reduction in post-op AKI, but no change in the need for dialysis or mortality. Although this was a large (>3500 subjects)...
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