Would you recommend nodal irradiation in a patient with breast cancer with a single positive sentinel node and a low Oncotype who does not receive chemotherapy?

Topics: Breast Cancer • Radiation Oncology

Answer from: Radiation Oncologist at Community Practice

Without knowing all the details, this sounds like a patient that may have been eligible for Z11 (early stage patients treated with BCS and SLN bx who were found to have 1-2 positive SLN then randomized to ALND vs no further surgery with all patients receiving at least tangents to breast). There was ...

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Radiation Oncologist at Swedish Covenant Hospital (Chicago IL)
The MA39 trial is studying this very question

Answer from: Radiation Oncologist at Academic Institution

Simul hit the high points: for these patients, important to breakdown single node with SLN vs. ALND. Also, lumpectomy vs. mastectomy. If SLN+ with no ALND, we typically rely on AMAROS regardless of lumpectomy and mastectomy and offer regional nodal irradiation with breast/chest wa...

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Radiation Oncologist at Lake Huron Medical Center
Yes, AMAROS also clouds the issue further! Wit...

Radiation Oncologist at Weill Cornell Medical College
agree with all of the above comments and risk fact...

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