Technically, based on the available clinical trial evidence, PFO closure is not indicated for patients over age 60 or for patients whose stroke was > 6 months ago. However, we frequently need to extrapolate from clinical trial populations to manage the patients we see in practice. Also, presumably, ...

Yes, PFO closure may be reasonable but several conditions should be met. First, the determination of the stroke mechanism should be made by a neurologist, particularly a vascular neurologist. Second, the interventional cardiologist's experience in PFO closure is important and he/she should evaluate ...