Would you recommend pharmacologic treatment with levothyroxine for a patient with subclinical hypothyroidism and CAD s/p stent placement even if the TSH is less than 10mIU/L, given a described association with reduced risk for major adverse cardiovascular events with treatment?

As always, the treatment should be individualized. The treatment of subclinical hypothyroidism can be very different in younger patients compared to the elderly. According to the European Thyroid Association, initially, if the serum TSH is elevated in the range of 4 to 10 but with a normal Free T4, ...

If the CAD has been corrected by the stent, there is no risk in treating subclinical hypothyroidism with Levothyroxine. Questions to ask the patient are if their angina sx have resolved after stent placement, whether they get angina with physical activity, and what level of physical activity they ca...