Topics:
Breast Cancer • Radiation Oncology • Medical Oncology • NCI-CCC Tumor Board Question • Moffitt Cancer Center • NCI-CCC Breast Tumor Board Question
Would you recommend PMRT for a patient with a right breast mastectomy with closest margin less than 0.1cm?
Answer from: Radiation Oncologist at Community Practice
I would consider this if there were other high risk factors like T2 disease, high grade or LVSI. In absence of these factors, favor systemic treatment alone. Here is one reference.
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Answer from: Radiation Oncologist at Academic Institution
If it's a T2N0 with close but negative margins (no tumor on ink), I do not offer PMRT in most cases. It can be considered in conjunction with factors such as triple negative/ER-, LVSI.
Answer from: Radiation Oncologist at Community Practice
Part of the decision-making process would depend on the location of the close margin. If it was posterior margin that was close (assuming no other adverse risk factors), then I would be much less likely to offer PMRT.