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Would you recommend starting finerenone for a patient with diabetic kidney disease who has marked improvement from severely increased albuminuria to moderately increased albuminuria following ARB and SGLT2i initiation?

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What is your approach to initiating finerenone in a patient with diabetic kidney disease whose albuminuria has improved from severely increased to moderately increased following optimization of ARB and SGLT2 inhibitor therapy?

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3 Answers
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Nephrology · Penn Medicine Cherry Hill
Answered on · Updated on

I would certainly discuss with the patient regarding potential benefits as well as risks. This is a joint decision matter, especially if finerenone leads to the need for potassium binders. Make sure first that the ARB dose is maximized with appropriate use of a diuretic.

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Nephrology · University Of California San Francisco Medical Center At Parnassus
Answered on

Yes, if the potassium and blood pressure allow it. The real question is whether there is an added benefit from finerenone compared to spironolactone. My personal belief is no, except that finerenone is much less likely to cause hyperkalemia.

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Nephrology · Indiana Nephrology And Internal Medicine
Answered on

Yes

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