Would you recommend tamoxifen x 5 years following mastectomy in a male with pure DCIS?
Answer from: Medical Oncologist at Academic Institution
I would not. The risk of developing contralateral breast cancer in a woman with DCIS is about 5% per decade, or 0.5% per year. At this level of risk, chemopreventive tamoxifen is an appropriate consideration. The risk of contralateral breast cancer in a man with DCIS is uncertain, but is almost cert...
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