Would you stop Dupixent in an asthma patient who has good asthma control and notes improvement in loss of smell, but shows notable eosinophil elevation after 4-5 doses of the medication?
Dupixent was started for asthma. Eosinophils rose from 880 to 1940 after 6-8 weeks of therapy.
Answer from: at Academic Institution
Transient eosinophilia has been reported in patients treated with Dupixent, likely related to downregulation of eotaxin and adhesion molecules resulting in impaired eosinophil migration into the tissues (Castro et al., PMID 29782217, Olaguibel et al., PMID 35522053). This phenomenon is typically see...
Comments
at Family Allergy And Asthma Maybe another explanation is that many patients wi...
at The Ohio State University Great question and discussion! For someone already...
at Baylor College of Medicine I will say that knowing that Dupixent causes some ...
at The Ohio State University Thanks for the follow-up, good to know. I have had...
at Kansas City Allergy And Asthma Associates Pa There are case reports of patients developing eosi...
Maybe another explanation is that many patients wi...
Great question and discussion! For someone already...
I will say that knowing that Dupixent causes some ...
Thanks for the follow-up, good to know. I have had...
There are case reports of patients developing eosi...