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Would you treat a hemochromatosis carrier with IV iron if they have iron deficiency anemia in conjunction with elevated ferritin?

Hb <11, low iron saturation (<10%), high ferritin (>900), and low reticulocyte hemoglobin equivalent.
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Would you treat a hemochromatosis carrier with IV iron if they have severe iron deficiency anemia in conjunction with elevated ferritin?

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1 Answer
Mednet Member
Mednet MemberInvited Expert
Hematology · Georgetown University School of Medicine
Answered on

This scenario, with numbers like these, suggests another underlying issue. A carrier of hemochromatosis cannot typically have a ferritin level of >900 due to hemochromatosis. The TSAT of <10% corroborates this statement. If this patient is real, they likely have an underlying inflammatory disorder ...

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