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Would you treat a patient with small cell lung cancer (limited to lung and mediastinum) but also with a malignant pleural effusion with upfront definitive thoracic chemoradiation?

If so, what would you include in the target and what dose?
2 Answers
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Radiation Oncology · Quillen VA Medical Center
Answered on

I would treat such a case as EXTENSIVE DISEASE. That means chemotherapy with 4 cycles of Plat/Etop, and restage with PET. If the pleural disease has gone by imaging or/and pleural tap, I would add thoracic radiotherapy 30 gy/10 fractions and PCI 2.5 gy X ten. If the pleural space remains positive, I...

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Radiation Oncology · Varian Medical Systems/Allegheny health network
Answered on

We would not treat like limited stage but this is subset of extensive stage if have nice response to chemo would add thoracic RT with PCI

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