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Would you treat rectal squamous cell carcinoma the same as rectal adenocarcinoma, stage for stage?

Any adjustments in terms of elective nodal coverage?
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How do you treat rectal squamous cell carcinoma?

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4 Answers
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Radiation Oncology · University of Nebraska Medical Center
Answered on

No, I will treat rectal squamous cell carcinoma the same as anal squamous cell carcinoma, with definitive chemoradiation with 5FU/mitomycin. If the cancer invades the posterior vaginal wall or prostate, I will also include external ilac nodes. If the tumor involves lower rectum/anus, I will also tre...

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Radiation Oncology · Rush University Medical Center
Answered on

Location is everything. If the tumor approaches the anal canal, I would treat like answered above, with combined chemo/RT appropriate for squamous cell cancer of the anus. However, if the tumor starts a significant distance from the dentate line, I would consider preoperative radiation and chemother...

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Radiation Oncology · Coastal Radiation Oncology
Answered on

I have received a number of referrals from gastroenterologists for patients with “rectal SCC”. DRE usually reveals a typical mass originating in the anal canal and bridging the dentate line. I believe the “mislabeling” may occur during colonoscopy, when these are viewed by a retroflexed colonoscope....

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Radiation Oncology · University of Florida
Answered on

CRT like anal SCC

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