Would you treat rectal squamous cell carcinoma the same as rectal adenocarcinoma, stage for stage?

Topics: Radiation Oncology • Gastrointestinal Cancers • Rectal Cancer • Anal Cancer • Medical Oncology

Any adjustments in terms of elective nodal coverage?

Answer from: Radiation Oncologist at Academic Institution

No, I will treat rectal squamous cell carcinoma the same as anal squamous cell carcinoma, with definitive chemoradiation with 5FU/mitomycin. If the cancer invades the posterior vaginal wall or prostate, I will also include external ilac nodes. If the tumor involves lower rectum/anus, I will also tre...

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Radiation Oncologist at Washington University School of Medicine
I would review carefully with pathology to make su...

Radiation Oncologist at Cancer Treatment Center at Hazleton
Treatment of the inguinal lymph nodes without anal...

Answer from: Radiation Oncologist at Academic Institution

Location is everything. If the tumor approaches the anal canal, I would treat like answered above, with combined chemo/RT appropriate for squamous cell cancer of the anus. However, if the tumor starts a significant distance from the dentate line, I would consider preoperative radiation and chemother...

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Medical Oncologist at Southern Cancer Center
I agree, but in addition to location, HPV status w...

Answer from: Radiation Oncologist at Community Practice

I have received a number of referrals from gastroenterologists for patients with “rectal SCC”. DRE usually reveals a typical mass originating in the anal canal and bridging the dentate line. I believe the “mislabeling” may occur during colonoscopy, when these are viewed by a ...

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Radiation Oncologist at Rush University Medical Center
The answers by @Chi Lin, @Krystyna D. Kiel, and @T...

Radiation Oncologist at Cancer Treatment Center at Hazleton
Though not replacing a physical exam, I would thin...

Answer from: Radiation Oncologist at Academic Institution

CRT like anal SCC

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