Would you treat Scedosporium growth in expectorated sputum in a patient with COPD, pulmonary hypertension, and bronchiectasis, who has chronic dyspnea with exertion, thick sputum production, negative bacterial cultures, and no signs of mold infection on a high resolution CT scan, with no other clinical symptoms of infection?

Answer from: at Community Practice

No, I would not. The patient described seems to be colonized with Scedosporium. There is no evidence of invasive disease, so I have no reason to think that antifungal treatment would provide them any benefit.

Comments

at Hurley Medical Center
The challenge is determining colonization vs infec...

at National Institute of Allergy and Infectious Diseases (NIAID)
I am definitely not an expert on bronchiectasis an...

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