Would you use a myeloablative or reduced intensity conditioning regiment for a pediatric or AYA patient who does not recover their counts after treatment for AML, but remains disease free?
Would you test for bone marrow failure syndromes before beginning the conditioning regimen?
Answer from: Medical Oncologist at Academic Institution
I would use a myeloablative regimen, if medically fit and eligible. In fact, I would worry that there is a residual disease (that you're unable to detect) behind the lack of CBC recovery which is another reason to use a myeloablative regimen.
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