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Would you use a PARP inhibitor as treatment for recurrent platinum-sensitive ovarian cancer with a RAD51 (or other moderate-penetration HRD germline) mutation?

Would your recommendation change if the patient was platinum-resistant?
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Do you treat patients with moderate-penetrance HRD germline mutations (such as RAD51) with PARP inhibitors in the recurrent, platinum-sensitive setting?

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1 Answer
Mednet Member
Mednet Member
Gynecologic Oncology · VA Boston Healthcare System
Answered on

Of course

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