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Topics:
Medical Oncology
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Hematology
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Internal Medicine
Would you use methotrexate to treat a small T-LGL clone (<650 cells/m3), with mild pancytopenia, and associated autoimmune disease such as systemic sclerosis?
Would a better alternative be consideration of a clinical trial with ruxolitinib?
Related Questions
If a bone marrow biopsy reveals mast cell leukemia, would you consider treating with avapritinib?
Given the data from SWOG 1826 suggesting that Nivo-AVD is likely the preferred regimen for advanced Hodgkin lymphoma patients, are there scenarios where alternative regimens may still be preferred?
Should you consider thromboprophylaxis, even for low-dose lenalidomide maintenance, post-autologous transplantation?
In an elderly transplant ineligible IDH1-mutated patient with AML, who is in remission after 6 cycles of azacitidine and ivosidenib, would you discontinue azacitidine after cycle 6 and continue maintenance ivosidenib until progression/toxicity or continue both azacitidine and ivosidenib?
How do you approach second-line options for relapsed myeloma after front-line quadruplet therapy?
What is your experience using sucrosomial iron for symptomatic iron deficient patients who are intolerant of ferrous sulfate and prefer an oral regimen?
How would you treat a patient with selective IgM deficiency on IVIG infusions with a new diagnosis of CLL?
Would an MPL variant mutation of unknown clinical significance be considered diagnostic of essential thrombocytosis in a patient with longstanding elevation in the platelet count, and for whom all secondary causes have been excluded?
How would you approach fertility preservation in a young patient with DLBCL requiring R-CHOP?
How would you manage a healthy 31 younger patient with nodular lymphocyte predominant Hodgkin lymphoma with severe hemolytic anemia but no other symptoms that responded to steroids?