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Would you use the pneumococcal conjugate-21 vaccine (Capvaxive) instead of the conjugate-20 (Prevnar-20) for routine vaccinations in immunosuppressed patients?

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2 Answers
Mednet Member
Mednet Member
Infectious Disease · Harbor - UCLA Medical Center

PCV-21 was recently approved by the FDA and supported by ACIP. At this early stage (August 2024), CDC has not finalized guidance on PCV-21, so we do not know how the vaccine schedule will be changed.

An important distinction is that PCV-21 covers different serotypes of pneumococcus, as outlined in t...

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Mednet Member
Mednet Member
Rheumatology · Uniformed Services University of the Health Sciences (USUHS)

PCV21 recently recommended by CDC and ACIP = NEW INFO: PCV21 is recommended for all adults 50 and older, and for those 19 and older with special risk factors...

The CDC now recommends PCV21, PCV20, or PCV15 (+PPSV23 a year later if got PCV15) to "all adults 50 years or older":

https://www.cdc.gov/pne...

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