How do you manage dose titration and nutrition to avoid sarcopenia when prescribing a GLP-1 receptor agonist in a frail older adult with MASLD?
Koutouratsas et al., PMID 42765724
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How do you manage dose titration and nutrition to avoid sarcopenia when prescribing a GLP-1 receptor agonist in a frail older adult with MASLD?
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2 Answers
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Endocrinology · Brigham And Womens Hospital Endocrinology
Answered on
GLP-1 and GLP-1/GIP receptor agonists as a class have been found to be effective in improving MASLD (Loomba et al., PMID 38856224) in patients with and without diabetes. This large class of drugs(more are on the way) also causes significant weight loss, and newer iterations may lower BMI into the no...
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Hepatology · Mayo Clinic
Answered on
Dose titration remains as is and as tolerated. If rapid weight loss, decrease dose. Ensure protein focused (aim higher end of needs) and mandatory resistance exercise.
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