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What infectious prophylaxis would you recommend in an infant with Wiskott-Aldrich syndrome during donor search and pre-transplant?

Especially considering if you are not planning to transplant for a year?
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What infectious prophylaxis measures do you take in a patient with Wiskott-Aldrich who has not yet undergone transplant?

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1 Answer
Mednet Member
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Pediatric Hematology/Oncology · University of Florida
Answered on

In infants with Wiskott-Aldrich syndrome, the degree of immune deficiency is variable and should be evaluated with a comprehensive assessment of both T-cell and B-cell immunity. Current testing typically includes lymphocyte subsets (CD3, CD4, CD8, CD19/20, NK cells), quantitative immunoglobulins (Ig...

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