Are there any biomarkers, imaging, or other clinical information that can be used to better choose effective therapies for super refractory status epilepticus?

SRSE is a syndrome not a diagnosis. The key determination is if this is immune-mediated, infectious, structural, metabolic, genetic, or drug/toxic-induced. For example, if the lumbar puncture shows significant pleocytosis, in the presence of flare changes in the medial temporal lobes, especially in the setting of fever/systemic signs, suspect viral/herpes encephalitis and start treatment. If lumbar puncture shows somewhat of a pleocytosis, elevated protein, plus-minus oligoclonal bands, and neural antibodies like anti-NMDA receptor encephalitis, LGI1, etc., perhaps preceded by a viral-like prodrome, coma, psychiatric or cognitive changes, then it would walk down the path of immune-mediated. MRI may or may not show limbic or medial temporal ...

Not that I know of.